Phillies vs. Mariners: Betting Odds, Predictions, and Key Details for August 19

The Philadelphia Phillies look to secure a series victory against the Seattle Mariners in an important interleague clash on Tuesday. Philadelphia triumphed with a 12-7 victory in the opening game on Monday. Currently, the Mariners (68-58) have dropped three consecutive matches and sport a 31-33 away record this season. In contrast, the Phillies (72-53) are riding a two-game winning streak with an impressive 38-21 home record in 2025.

Scheduled for 6:45 p.m. ET at Citizens Bank Park in Philadelphia, the Phillies have won four of the last six encounters against the Mariners. The Phillies are favored at -205 on the money line (risk $205 to win $100), and the over/under is set at 8 runs. Before placing any bets, check out the MLB predictions and betting advice from SportsLine’s proven model.

The SportsLine Projection Model simulates every MLB game 10,000 times and is currently 33-24 on top-rated MLB money-line picks this season.

Why the Phillies Can Win

Cristopher Sanchez (11-4, 2.45 ERA) will be the starting pitcher for Philadelphia. Over 24 starts this season, he has pitched 150.2 innings, permitting 128 hits, 41 earned runs, and 36 walks while striking out 157 batters. He has clinched six wins in his last eight decisions.

First Baseman Bryce Harper is a key player for the Phillies, batting .262 with 28 doubles, 21 home runs, 58 RBIs, and 56 runs in 97 games this season. In his career against Seattle, he has a .385 average with four doubles and four home runs. He recently performed well against Seattle, going 3-for-6 with two home runs in the previous match.

Why the Mariners Can Win

Bryce Miller (2-5, 5.73 ERA) is expected to start on the mound for Seattle. In ten starts this year, he has pitched 48.2 innings, giving up 31 earned runs. He recently faced the Los Angeles Angels, conceding five earned runs in five innings.

Catcher Cal Raleigh has emerged as a significant offensive contributor, batting .249 with 18 doubles and leading the MLB with 47 home runs among his 123 games played. His recent performance includes a solid 2-for-5 showing with a home run against the New York Mets, enhancing his reputation as a key player for the Mariners.

Making Picks for Mariners vs. Phillies

The SportsLine model is projecting a high-scoring match and highlights one side of the money line that presents excellent value. Visit SportsLine to explore the full depth of these MLB picks.