Overview of Week 1 College Football Matches

The kick-off for the 2025 college football season is upon us, featuring a thrilling schedule around the weekend. Highlighted this week are three top-10 matchups: Texas takes on Ohio State, LSU faces Clemson, and Notre Dame will challenge Miami.

Key Matchups

• Texas vs Ohio State (-2.5)
• LSU vs Clemson (-4)
• Notre Dame vs Miami (+2.5)

In various games, the Penn State Nittany Lions come in as 44.5-point favorites against Nevada, while the Georgia Bulldogs lead with a 39.5-point advantage versus Marshall. With no in-season data available, predicting these matchups can be tricky.

Top Predictions From SportsLine’s Model

One standout prediction is that Alabama, currently ranked No. 8, is set to convincingly beat Florida State with a 13.5-point spread. The Tide boasts a significant winning streak in season openers, solidifying their strong historical performance against top-tier teams.

FSU’s performance has suffered after a dismal record last season, making their chances against Alabama seem grim. According to insights from the model, Alabama is projected to clinch victory by at least two touchdowns.

For further predictions and detailed betting insights, refer to the SportsLine model which has shown impressive returns for bettors since its inception. See full details on college football odds below:

Upcoming Week 1 Odds

• Thursday, Aug. 28: Boise State vs South Florida (+6, 63.5)
• Friday, Aug. 29: Illinois vs Western Illinois (+46.5, 63.5)
• Saturday, Aug. 30: Texas vs Ohio State (-2.5, 47.5)
• Sunday, Aug. 31: South Carolina vs Virginia Tech (+7.5, 50.5)
• Monday, Sept. 1: TCU vs North Carolina (+3, 58.5)

(Odds are subject to change)