The NFL preseason has concluded, shifting all focus to the upcoming Week 1 NFL games, just a week away from starting. The action kicks off with the Cowboys facing the Eagles in the highly anticipated 2025 NFL Kickoff Game on Thursday, followed by the Chiefs taking on the Chargers in Brazil on Friday. There are thirteen games scheduled for Sunday, culminating in the Vikings battling the Bears on Monday.

Key odds for Week 1 have emerged, with the Eagles favored by -7.5 against the Cowboys, a movement attributed to the recent Micah Parsons trade, while the Vikings are positioned at -1.5 against Chicago. Notably, the Bills are set as -1.5 favorites against the Ravens in a Sunday Night showdown between two AFC contenders.

Eric Cohen, a seasoned SportsLine expert, examines the full slate of NFL action for Week 1, providing score predictions and rationale behind his forecasts for each matchup. Cohen’s impressive track record includes finishing the 2024-25 season with a remarkable 190-95 straight-up pick record (69%), proving profitable for bettors engaging with his insights.

For more detailed picks, visit SportsLine to see Cohen’s scores predictions and the best bets for the onset of the NFL season.