
A highly anticipated matchup to kick off the 2025 college football season sees the No. 9 LSU Tigers visiting the No. 4 Clemson Tigers.
Clemson concluded last year with a record of 10-4 but faced elimination in the College Football Playoff’s first round against Texas (38-24). Conversely, LSU finished 2024 with a 9-4 record, securing a victory over Baylor (44-31) in the Texas Bowl.
Kickoff Information
The game takes place at Memorial Stadium in Clemson, with a kickoff time at 7:30 p.m. ET. According to the latest consensus from SportsLine, Clemson is favored by 4 points, with a total points over/under set at 57.5.
SportsLine Model Predictions:
- LSU +4
- Over 57.5 total points
- Clemson Over 27.5
- Parlay odds +360
In 2024, LSU quarterback Garrett Nussmeier returns for his senior year after throwing for 4,052 yards and 29 touchdowns. The model has predicted that LSU will cover the spread 65% of the time in simulations.
Clemson’s lineup showcases quarterback Cade Klubnik alongside returning top receivers. The model expects a combined total of 64 points this Saturday.
Continue to follow SportsLine for updates on Week 1 matchups, featuring expert betting insights and analysis on college football.