The No. 8 Alabama Crimson Tide commence their 2025 season against the Florida State Seminoles this Saturday. Entering Week 1, Kalen DeBoer’s team is looking to improve after a disappointing 9-4 season.

Kickoff will be at 3:30 p.m. ET in Doak Campbell Stadium. In the latest odds, the Crimson Tide are favored by 13.5 points, with a total points over-under set at 50.5. Before making your picks, check out the predictions from SportsLine’s model, which has simulated the game 10,000 times.

Key Picks for the Match:

• Alabama -13.5: Historical data shows that Alabama has a strong chance of covering the spread.
• Alabama Over 31.5: With a formidable offense, Alabama is projected to score around 33 points.
• Florida State Under 17.5: Florida State’s scoring has consistently dipped below this threshold.

Want more college football insight for Week 1? Get detailed predictions and betting tips based on model simulations for every game.