The Cincinnati Bengals are set to kick off their 2025 NFL season alongside the Cleveland Browns, with a playoff absence last year still fresh in memory. Bengals’ quarterback Joe Burrow, who had a nearly MVP-caliber performance, faces off against the Browns who named Joe Flacco as their starter. Cincinnati is favored by 5.5 points, despite Burrow’s mixed history against Cleveland (3-5 record). Will the Bengals deliver against the spread in this matchup?
Meanwhile, when the Pittsburgh Steelers visit the New York Jets, it will be a reunion for Aaron Rodgers. The Steelers are slight favorites at 2.5 points, with an over/under set at 38.5, marking the lowest total for the week. Which team should be included in your Week 1 betting choices?
Before confirming any Week 1 picks or NFL parlays, check out SportsLine’s betting predictions derived from their advanced simulation model.
This model, which predicts every NFL game through 10,000 simulations, boasts an impressive record, having gained over $7,000 for $100 players since its inception. Following its picks can lead to substantial returns, particularly given its successful 31-15 record with top-rated bets last year.
The model has identified five prime NFL betting opportunities for Week 1, presenting the chance for a substantial payout with a nearly 25-1 parlay if bets are strung together successfully.
Top Week 1 Picks
A standout pick is the Washington Commanders, favored by 6 points against the New York Giants. Having reached the NFC Championship last season, they are riding momentum, winning seven straight games. Their quarterback, Jayden Daniels, has shown remarkable performance, completing 69% of passes and achieving notable stats in their playoff run. With a new contract solidifying wide receiver Terry McLaurin’s position in the lineup, the Commanders are projected to cover the spread in over 60% of simulations, making this a strong A-rated bet.
For other betting opportunities this week, check out how the model expects the lines to shift and where it identifies discrepancies, particularly regarding an unexpected underdog it believes will win outright.
What are the major Week 1 betting chances and which NFL matchups are primed for potential payouts? Visit SportsLine for insights into top bets from a model renowned for its strong follow through on previous performance.
