The reigning Super Bowl champions, Philadelphia Eagles, are set to kick off their season against the Dallas Cowboys in the highly anticipated 2025 NFL Kickoff Game on Thursday, September 4. Last season, the Eagles recorded an impressive 14-3 and concluded their playoff stretch with a decisive 40-22 victory over Kansas City in the Super Bowl. In contrast, the Cowboys, having traded Micah Parsons to the Packers, missed the playoffs last season with a 7-10 record, largely due to Dak Prescott battling injuries that limited him to just eight games.
This matchup marks the first Week 1 confrontation between these long-time rivals since 2000.
Kickoff is scheduled for 8:20 PM ET at Lincoln Financial Field in Philadelphia, with the Eagles favored by 7.5 points according to the latest odds from FanDuel Sportsbook. The over/under is set at 47.5 points.
Before finalizing any bets on the Cowboys vs. Eagles, consider checking the insights from the SportsLine projection model.
Why the Eagles can cover
In their previous season, the Eagles dominated the series against Dallas, winning both matchups with a staggering combined score of 75-13. Saquon Barkley, who led the NFL in rushing attempts, yards, and average yards per game, looks to leverage a vulnerable Dallas defense that struggled against the run last season. Jalen Hurts also had a solid running contribution, and Philadelphia boasts an 11-game home winning streak while covering the spread in six of their last seven NFC East games.
Why the Cowboys can cover
With Dak Prescott returning, the Cowboys are optimistic about their offense. They’ve signed George Pickens, known for his impressive yards per reception, to complement CeeDee Lamb as a primary target. With a competitive edge this season, the Cowboys will look to bounce back and redeem themselves from their previous losses to the Eagles.
How to make Cowboys vs. Eagles picks
The projection model indicates that the point total is likely to go ‘Over’, with one side of the spread succeeding in nearly 60% of simulations. For more details, visit SportsLine to discover which side is favored.
