
The Week 1 NFL schedule is just days away, with numerous games featuring tight spreads of three points or less. Notable matchups include:
- Chiefs vs. Chargers (+3)
- Buccaneers vs. Falcons (+2.5)
- Dolphins vs. Colts (-1)
- Steelers vs. Jets (+2.5)
Only two games feature spreads exceeding seven points. In one, Cam Ward will make his professional debut as his Titans face an 8-point deficit against the Broncos, closely followed by the Cowboys at +8.5 against the Eagles.
For those keen on making informed betting decisions in the first week of the 2025 NFL season, the updated odds are outlined below.
Key Predictions
One of the model’s strongest picks suggests that the Bengals (-5.5, 47.5) will secure a win against the Browns. Uncertainty surrounds Cleveland’s quarterback situation, which may not ultimately matter, given Joe Burrow’s outstanding previous season with 4,918 passing yards and 43 touchdowns. Keeping talents like Ja’Marr Chase and Tee Higgins on board retains their formidable passing offense.
Cincinnati’s offense is likely to outscore Cleveland, which struggled last year, finishing last in scoring. Points are projected for Cincinnati more than 50% of the time if they meet the spread.
Another sharp forecast has the Packers (-2.5, 47.5) covering against the Lions. Following their acquisition of Micah Parsons, Green Bay’s line has shifted to favor them by a point. Trends suggest that pressure on Lions’ quarterback Jared Goff could lead to turnovers, and the Packers’ defense is primed to capitalize, clearly setting them up for a projected win.
The betting lines for other Week 1 games, along with picks and predictions detail, can be found through the links below.