The highly anticipated 2025 NFL season kicks off with a significant NFC East matchup featuring the Dallas Cowboys facing the defending Super Bowl champions, the Philadelphia Eagles. The Eagles are 8.5 point favorites with an over/under of 47.5.

Since 2010, the Cowboys and Eagles have jointly secured 11 NFC East division titles. A returning and healthy Dak Prescott is set to lead the Cowboys, who recently traded star defensive end Micah Parsons to the Green Bay Packers post a long-lasting contract dispute. Philadelphia enters the game with notable expectations.

Player Prop Expectations

The Cowboys vs Eagles prop odds have Saquon Barkley set at a total rushing yard expectation of 96.5, while Prescott’s passing yard total is pegged at 243.5. Prior to placing any bets for the kickoff game, take a look at the predictions powered by SportsLine’s Machine Learning model covered in the analysis.

Key Prop Bets

The SportsLine Machine Learning model forecasts that Dak Prescott will fall short on 243.5 passing yards (-142 at DraftKings), rating this as a 3.5-star play. Historically, Prescott has underperformed this total in four out of his last five games, averaging around 225.4 passing yards.

Predictive analytics suggest that as Dallas is anticipated to trail, Prescott will be tasked with passing frequently, averaging an estimated 33 attempts, which is just shy of the 36.5 line set for attempts.

For further prop bets and exclusive insights, refer to SportsLine’s recommended prop picks as predictions from the Machine Learning model are shared above.