The 2025 NFL season kicks off on Thursday, September 4, when the Philadelphia Eagles host the Dallas Cowboys at Lincoln Financial Field, with kickoff set for 8:20 p.m. ET and Philadelphia favored by 8.5 points. The over/under is 47.5 points. This matchup presents a powerful DFS player pool, led by fantasy icons like Jalen Hurts, Saquon Barkley, CeeDee Lamb, Dak Prescott, and A.J. Brown.

DFS players must thoughtfully consider whether to include both Hurts and Prescott in their lineups, which could significantly impact salary allocation. Finding undervalued players at budget-friendly prices is essential for crafting effective NFL DFS strategies, especially amid so many star players.

Prior to setting lineups on platforms like DraftKings and FanDuel, make sure to explore insights and strategies from expert Jimmie Kaylor, who has notable accomplishments in NFL DFS. Kaylor’s expertise could provide the edge needed for your fantasy success this season.

Top NFL DFS Picks and Strategies

One standout DFS recommendation from Kaylor is Philadelphia’s Saquon Barkley, who had a stellar performance last season, rushing for 2,005 yards and 13 touchdowns. His consistent excellence has placed him at the forefront of the fantasy draft rankings.

Kaylor also emphasizes the need to feature Eagles quarterback Jalen Hurts in your lineup due to his impressive dual-threat capabilities. Hurts, who was named Super Bowl MVP, had significant success against the Cowboys last season and is expected to be a key contributor once again.

Kaylor has formulated a strategic approach, including incorporating some undervalued players that could lead to significant gains during the Kickoff Game.

To see more of Kaylor’s optimal picks, strategies, and recommended player stacks, revisit SportsLine for complete analysis.