The Week 1 NFL schedule is set to kick off in just one day, with many games lined up with a spread of a field goal or less. Key matchups to bet on include:

• Chiefs vs. Chargers (+3)
• Buccaneers vs. Falcons (+2.5)
• Dolphins vs. Colts (-1)
• Steelers vs. Jets (+2.5)

Two games feature spreads of more than a touchdown: the Titans, led by Cam Ward in his debut, are 7.5-point underdogs against the Broncos, while the Cowboys face the Eagles as 8.5-point underdogs.

To ensure successful betting on this first week of games, check out the updated lines below and detailed advice from SportsLine’s simulation model, which runs 10,000 simulations to help even the most hesitant bettor find confidence.

Top Week 1 Predictions:

• The Bengals are favored (-5.5) to cover against the Browns. Despite uncertainty surrounding Cleveland’s quarterback situation, Cincinnati’s Joe Burrow, who led the NFL last season in yards and touchdowns, is expected to shine with his receiving corps intact.

• The Packers are also predicted to cover at home (-2.5) against the Lions after their recent acquisition of Micah Parsons.

For further insights and every match’s betting odds, check SportsLine.