The NFL Week 1 schedule has commenced, with teams eager to establish dominance early in the season. The Green Bay Packers, after a playoff run in 2024 ended against the Philadelphia Eagles in the Wild Card Round, are set to face the Detroit Lions in a vital NFC North clash on Sunday at 4:25 p.m. ET. Recent statistics show Detroit’s impressive performance on the road, clocking in at 8-0 in their last outings, yet they find themselves as 2.5-point underdogs this weekend. According to SportsLine’s predictions, the Packers should prevail at Lambeau Field, covering the spread in a majority of simulations.
Additionally, the model forecasts the Jaguars (-3.5) will clinch victory at home over the Panthers, and anticipates an Over (45.5) in the match between the Giants and Commanders, with nearly 70% of simulations supporting this outcome.
Best Bets for NFL Week 1:
- Packers (-2.5) vs. Lions
- Over 45.5 points for Giants vs. Commanders
- Jaguars (-3.5) vs. Panthers
Should you combine all three picks into a Week 1 parlay, it would yield an enticing +595 payout if placed on DraftKings.
Packers -2.5 vs. Lions
Despite the Lions’ recent robustness under head coach Dan Campbell, the Packers are equipped to achieve victory. Josh Jacobs’ last season showcased his prowess with 1,329 rushing yards and 15 touchdowns, and is expected to be pivotal against a Detroit defense that is vulnerable.
Giants vs. Commanders: Over 45.5 Points
Russell Wilson joins the Giants’ offensive setup, adding experience to a lineup with dynamic playmakers like Malik Nabers. On the opposing side, the Commanders plan to counter with talents such as Terry McLaurin and Deebo Samuel. Historical trends suggest scoring will be robust, favoring the Over in simulations.
Jaguars -3.5 vs. Panthers
The Panthers have faltered in away games, and the model suggests they will struggle again, especially given their last meeting with the Jaguars resulted in a 26-0 defeat.
