Week 1 of the 2025 NFL season has come and gone, and the unfolding of Week 2 has already highlighted several player injuries that could shift betting trends. As bettors prepare for 15 games this week, keeping an eye on injury reports is crucial, especially for high-impact players.
Below are some key injuries to watch, including updates that may influence betting odds:
New York Giants vs Dallas Cowboys (1 p.m. ET)
- DaRon Bland (DAL CB, foot, out)
- Andrew Thomas (NYG OT, foot, doubtful)
- Wan’Dale Robinson (NYG WR, ankle, questionable)
The Giants may miss their left tackle, adding pressure to the already challenged Dallas defense.
Seattle Seahawks vs Pittsburgh Steelers (1 p.m. ET)
- Joey Porter Jr. (PITT CB, hamstring, out)
- DeShon Elliott (PITT S, knee, out)
- Devon Witherspoon (SEA CB, knee, doubtful)
- Nick Emmanwori (SEA S, ankle, out)
Both teams are facing serious defensive challenges, with key players sidelined.
Buffalo Bills vs New York Jets (1 p.m. ET)
- Ed Oliver (BUFF DT, ankle, out)
- Tre’Davious White (BUFF CB, groin, questionable)
- Taron Johnson (BUFF CB, quad, questionable)
Injuries on Buffalo’s defensive line may leave the Jets scrambling for opportunities.
San Francisco 49ers vs New Orleans Saints (1 p.m. ET)
- Brock Purdy (SF QB, toe, out)
- George Kittle (SF TE, injured reserve)
Without Purdy and Kittle, the 49ers’ offense is set to rely on secondary options.
Carolina Panthers vs Arizona Cardinals (4:05 p.m. ET)
- Ikem Ekwonu (CAR OT, questionable)
- Will Hernandez (AZ OG, knee, questionable)
Offensive line struggles on both sides could influence the ground game’s effectiveness.
Tampa Bay Buccaneers vs Houston Texans (7 p.m. ET, Monday)
- Christian Kirk (HOU WR, hamstring, TBD)
- Chris Godwin (TB WR, ankle, TBD)
Both teams will look to capitalize with favorable matchups amidst a backdrop of injuries.
As always, keep an eye on the latest injury updates to make informed betting decisions.
