
AFC West rivals are set to clash in Las Vegas as the Las Vegas Raiders prepare to host the Los Angeles Chargers for Week 2 of the NFL season. The Chargers come into this matchup with a 1-0 record following a thrilling 27-21 victory over the Kansas City Chiefs during the NFL Sao Paulo game. The Raiders are also off to a solid start, having secured a 20-13 comeback win against the New England Patriots.
Kickoff is scheduled for 10 p.m. ET at Allegiant Stadium. As per the latest betting odds, the Chargers are favored by 3.5 points, with the over/under set at 46.5. The betting line indicates Los Angeles is a -185 favorite (risking $185 to win $100), while the Raiders stand at +154 underdogs (risking $100 to win $154). Before placing any bets on the Chargers vs. Raiders game, make sure to check out what the SportsLine projection model has to say.
This advanced model has successfully simulated every NFL game 10,000 times and has earned more than $7,000 for $100 players on top-rated NFL picks since inception. Currently, the model is on a 33-17 hot streak regarding top-rated picks since 2024.
In terms of players to watch, Justin Herbert excelled against Kansas City, throwing for 318 yards and three touchdowns. With a receiving team that includes Ladd McConkey, Quentin Johnston, and Keenan Allen, expect the Chargers to continue their offensive momentum against a Raiders defense that allowed 276 passing yards in their season opener.
On the flip side, the Raiders will aim to keep up with the Chargers’ pace. Their new offense delivered 389 total yards against the Patriots last week and will face a Chargers defense that allowed 347 total yards to Kansas City. This sets the stage for Geno Smith, who recorded 210 passing yards and two touchdowns in his last encounter versus Los Angeles. Despite permitting only 98 rushing yards last week, the Chargers will face a more significant challenge against Ashton Jeanty, making for an exciting Monday night matchup.
For those looking for further betting insights, the model is leaning towards an under total and highlights one side of the spread that hits over 50% of the time. Who stands a chance of winning on Monday night? Be sure to visit SportsLine for in-depth picks from the projections model that has proven its prowess in past seasons.