The Inside the Lines team utilizes a refined NFL model to present the top betting options leading into the Dolphins versus Bills matchup.

The SportsLine Projection Model, engineered by the Inside the Lines team, forecasts optimal wagers, such as:

Best Main Market Bet: Bills -12.5 (-110)

The Bills have shown resilience, covering a significant spread against the Jets in their last game. With Miami’s recent inconsistency, betting on Buffalo to win handily is advised.

James Cook Anytime Touchdown -172 (Caesars)

With the Bills likely to score over 30 points, placing a bet on James Cook for a touchdown feels almost guaranteed. He has maintained a 76% scoring rate in the past season.

Keon Coleman Over 42.5 Receiving Yards (-114 at FanDuel)

With Miami’s weakened secondary, Coleman is projected to exceed his average receiving yards significantly.

Tua Tagovailoa Over 0.5 Pass Interception (-160 at BetMGM)

With a high chance of throwing interceptions this season, expect Tua to potentially add another to his tally as the Dolphins play catch-up.