The Colorado Buffaloes (1-2) will host the Wyoming Cowboys (2-1) at Folsom Field in Boulder this Saturday. After a disappointing 36-20 defeat to Houston in their Big 12 debut, the Buffs aim to regain their footing. Coach Deion Sanders has yet to confirm whether Kaidon Salter or Ryan Staub will start at quarterback, although it appears Salter is in contention for the position. Wyoming comes into the game also seeking redemption after a lopsided 31-6 loss to Utah.

Kickoff is scheduled for 10:15 p.m. ET, with Colorado being favored by 11.5 points and the total set at 45.5 points. For comprehensive insights, make sure to check out expert picks from Jimmie Kaylor.

Why Colorado Can Cover

The Buffs are undergoing a tough season as they navigate early challenges with a 1-2 overall record. The team struggles at quarterback since previous stars Shedeur Sanders and Travis Hunter have moved to the NFL. The defense allows 23.3 points per game, with top players like Keon Colbert leading in tackles.

Why Wyoming Can Cover

Coach Jay Sawvel leads Wyoming to a respectable 2-1 start. Their offense averages 344.7 total yards with a solid ground game contributing to their efforts. The defense has been strong, permitting only 16 points per game, aided by standout players like Brayden Johnson and a formidable secondary.

Overview of Game Odds

Spread	Colorado -11.5
Over/Under	45.5 points
Money Line	Colorado -476, Wyoming +361

Kaylor has crunched the numbers and believes the total points will exceed expectations in this matchup. He’s identified a crucial X-factor that may decide this game. Check SportsLine for an insider’s edge on both teams’ strategies and maximizing betting opportunities.