2025 College Football Week 5 Predictions: Expert Picks and Odds
College Football/Sports

2025 College Football Week 5 Predictions: Expert Picks and Odds

Explore top college football predictions for Week 5, including expert insights on key matchups and betting odds.

The Week 5 college football slate promises exciting matchups influencing the playoff race. Latest odds show No. 4 LSU as a 1.5-point underdog against No. 13 Ole Miss, No. 3 Penn State is favored by 3.5 points versus No. 6 Oregon, and No. 5 Georgia is a 3-point favorite against No. 17 Alabama.

Best Bets for Week 5
Before placing any bets, check expert picks from Thomas Casale.

Having appeared frequently on national platforms discussing college sports, Casale brings over 30 years of sports betting experience. He currently stands at 9-5 for the season, boasting a 3-0 record in Week 4, and an impressive 22-11 run in his best bets column.

He emphasizes that backing No. 3 Penn State against No. 6 Oregon is a solid move, citing:

“This is a good spot to back Penn State. With their experienced roster, they are in a favorable position against an Oregon team yet to prove themselves against a top-tier opponent.”

For exclusive picks, sign up at SportsLine and utilize promo code CHAMPIONSHIP for a discounted initial month.

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