2025 NFL Week 4: Seahawks vs. Cardinals Predictions and Betting Odds
Football/Sports

2025 NFL Week 4: Seahawks vs. Cardinals Predictions and Betting Odds

A detailed look at the upcoming Thursday Night Football matchup between the Seattle Seahawks and Arizona Cardinals, including predictions, odds, and player insights.

Matchup Overview

An NFC West showdown unfolds as the Seattle Seahawks face the Arizona Cardinals in this Week 4 Thursday Night Football game. With both teams sitting at a 2-1 record, the Seahawks are entering with momentum after securing back-to-back victories, including a dominating 44-13 win against the Saints.

Meanwhile, Arizona is looking to rebound after a narrow loss to San Francisco, falling 16-15. The Seahawks have historically dominated this rivalry, winning the last seven encounters.

Game Details

Kickoff occurs at 8:15 p.m. ET at State Farm Stadium in Glendale, Arizona. The latest betting odds indicate Seattle as the 1.5-point favorite, with an over/under of 43.5 total points. Before placing any bets, check what insights the SportsLine projection model offers.

Key Players

  • Seattle Seahawks: Sam Darnold has shown proficiency against the spread, sitting at a 65% cover rate. Meanwhile, the Seahawks defense remains formidable, having not allowed a rushing touchdown yet this season.
  • Arizona Cardinals: Despite James Conner’s season-ending injury, the Cardinals are poised to utilize Trey Benson effectively, who has an impressive 6.0 yards per carry average. Kyler Murray also adds depth to their running game with 5.4 yards per rush.

Predictions

The modeling system used by SportsLine predicts confidence in this matchup, anticipating an ‘Over’ on total points, and suggesting that one side of the spread will hit significantly more times than not. For a deep dive into who’s expected to win and the statistical backing behind it, visit SportsLine for detailed coverage.

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