
The upcoming matchup features the Detroit Lions (3-1) against the Cincinnati Bengals (2-2) for NFL Week 5. The Lions are on a three-game winning streak, highlighted by a decisive 34-10 victory over the Cleveland Browns last week. In contrast, the Bengals have struggled following Joe Burrow’s turf toe injury, suffering two consecutive defeats, including a heavy loss to the Broncos (28-3 on September 29).
Kickoff is at 4:25 p.m. ET from Paycor Stadium in Cincinnati. The latest odds from DraftKings place the Lions as 10.5-point favorites, with an over/under of 49.5 points. The Lions’ money line stands at -550, while the Bengals are at +410.
Before placing any bets on this game, check out the predictions generated by the SportsLine Projection Model. This model has successfully simulated every NFL game 10,000 times and has a proven track record of profitability for bettors.
Latest Betting Insights:
- Lions -10.5: The Lions have shown significant strength with double-digit victories recently. They stand at 2-0 against the spread (ATS) following a win and 3-1 ATS this season. Their opponent has been plagued by poor performances, which the model predicts will continue.
- Over 49.5 points: The Lions rank high in total offense, having scored over 34 points in their last three outings, which includes key player Amon-Ra St. Brown leading the team. Despite the Bengals’ recent struggles, talented players remain that could help push the score up. The model forecasts the Over hitting in 52% of simulations.
For more in-depth analysis and additional recommendations for NFL Week 5, visit the SportsLine Projection Model picks.


