The matchup between the Colorado Buffaloes and the TCU Horned Frogs kicks off this Saturday, with both teams looking for their opening win in Big 12 play. Colorado is reeling from a recent loss against BYU (24-21), whereas TCU also seeks a rebound after falling to Arizona State (27-24) in Week 5. Currently, the Buffaloes sit at 2-3 overall and are winless on the road this season, while the Horned Frogs hold a 3-1 record with a perfect home game streak.

Kickoff is set for 7:30 PM ET at Amon G. Carter Stadium in Fort Worth, Texas, with TCU favored at 13.5 points according to the latest odds from SportsLine consensus, with an over/under set at 57.5 points.

Why TCU has an edge: Senior quarterback Josh Hoover, in his fourth season, has amassed impressive stats this year, averaging 66.7% in completed passes, totaling 1,242 yards and 11 touchdowns. A highlight was his 379 yards and five touchdowns performance against SMU on Sept. 20.

The Horned Frogs also benefit from standout receiver Eric McAlister, who leads his team with 320 receiving yards despite a quiet last game.

Why Colorado can compete: Transitioning from Liberty, Kaidon Salter is managing Colorado’s offense, with 684 passing yards, five touchdowns, and 202 rushing yards this season. He has shown potential in recent games, notably a 304-yard outing against Wyoming.

Running back Micah Welch adds to the rushing attack with solid performances over the season despite recent struggles.

For those interested, you can find updated betting picks through the links provided.