
NFL Week 7 2025 Preview: Best Bets and Predictions for Colts vs. Chargers, Broncos vs. Giants
Summary
This Sunday, the NFL schedule includes four games starting at 4 p.m. ET, headlined by a significant matchup between the Indianapolis Colts and the Los Angeles Chargers.
Key Matchup: Colts vs. Chargers
- The Colts come into this game with an impressive start to the season, boasting a record of 5-1 after a recent victory over the Cardinals. Meanwhile, the Chargers have a record of 4-2 after edging the Dolphins in their last game.
- Notably, the Chargers are 0-4 against the spread in their previous outings as favorites. The current betting line favors the Chargers by 1.5 points, with an over/under set at 48.5 points.
- The SportsLine model favors the Colts to win and cover the spread in 54% of simulations, while projecting them to win straight-up 51% of the time.
Predictions for Other Games
- Broncos vs. Giants: The Broncos are favored by 7 points. The model indicates that they will likely cover the spread in about 56% of simulations.
- Cowboys vs. Commanders: The total points is projected to exceed 54.5, which has occurred in 65% of simulations.
Want more insight?
To make the best betting decisions, check out the model’s full range of picks as part of its predictive analysis, which has consistently delivered strong results in NFL betting for multiple seasons.


