Where to watch 49ers vs. Texans: TV channel, live stream, prediction, pick, odds, spread
The injury-ravaged 49ers will look to keep pace in the NFC West with a win against the Texans
The Texans will host the 49ers in a battle of teams that aren’t currently operating at full strength. It’s safe to say that San Francisco has been heavily impacted by the injury bug in 2025. Brock Purdy, Brandon Aiyuk, Fred Warner, and Ricky Pearsall are just some of the 49ers who are currently sidelined. Still, San Francisco has managed to produce a 5-2 record. The 49ers came away with a hard-fought 20-10 win against the Atlanta Falcons in Week 7.
Meanwhile, the Texans haven’t been as fortunate to begin the 2025 campaign. Houston has started 2-4 and is fresh off a 27-19 loss to the Seattle Seahawks. To make matters worse, they might be without star wide receiver Nico Collins, who suffered a concussion against the Seahawks.
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Where to watch 49ers vs. Texans live
- Date: Sunday, Oct. 26 | Time: 1 p.m. ET
- Where: NRG Stadium – Houston, Texas
- TV: Fox | Stream: Fubo (try for free)
- Follow: CBS Sports App
- Odds: Texans -1.5; O/U 41.5 (via FanDuel)
49ers vs. Texans: Need to know
- San Francisco must keep feeding McCaffrey. The 49ers definitely missed star running back Christian McCaffrey during last season as he was limited to just four games due to injury. Entering Week 8, McCaffrey has paced San Francisco’s offense and leads the NFL with 981 scrimmage yards.
- Jones to remain under center. Purdy has been dealing with a toe injury that has sidelined the 49ers starting quarterback for five games. Mac Jones hasn’t been flashy, but has played well in relief of Purdy. The former first-round pick is completing 67.0% of his passes for 1,404 yards to go along with six touchdowns.
- Texans could be shorthanded at wide receiver. Entering the season, the Texans were already at a disadvantage at the wide receiver position. Veteran receiver Christian Kirk has been limited to three games this season due to injury. Kirk is currently questionable for Sunday’s contest, as is the status of star wideout Nico Collins.
49ers vs. Texans pick, prediction
This has the potential to be one of the lower-scoring games of Week 8. It’s no secret that the 49ers are extremely banged up, but still have the potential to pull off a narrow upset on the road. Jones continues to excel in Purdy’s absence, and the offense will do just enough to win. Pick: 49ers +1.5, Under 41.5
