The NFL’s Week 8 wraps up with an exciting cross-conference battle featuring the Kansas City Chiefs and the Washington Commanders on Monday Night Football. Kickoff at GEHA Field at Arrowhead Stadium is set for 8:15 p.m. ET.

With an over/under of 48 points, this matchup showcases a deep pool of NFL DFS talent, featuring names like Patrick Mahomes, Travis Kelce, Rashee Rice, Deebo Samuel, and Terry McLaurin. Notably, Samuel and McLaurin are overcoming injuries, while Washington will miss quarterback Jayden Daniels due to a hamstring issue.

Key DFS Picks for Chiefs vs. Commanders

One of Kaylor’s leading DFS selections is Chiefs quarterback Patrick Mahomes, who is solidifying his legacy as one of the greatest quarterbacks in the NFL. In the 2024 season, he threw for 3,928 yards, securing 26 touchdowns against 11 interceptions.

Furthermore, Mahomes has thrown for 1,800 yards and 14 touchdowns in the first seven games of the 2025 season, demonstrating increased efficiency and control.

Samuel is another crucial player Kaylor suggests considering; the former 49er had a good start with the Commanders, tallying 34 catches for 315 yards and three touchdowns this season.

For comprehensive DFS strategies and insights from Kaylor, make sure to check out his expert analysis.