
Celtics and Cavaliers Clash: Predictions and Odds for October 29, 2025
Get insights on the NBA matchup featuring the Celtics and Cavaliers, including predictions, odds, and betting advice.
The top two seeds from last year’s Eastern Conference face off on this Wednesday’s NBA schedule. The Cleveland Cavaliers will visit the Boston Celtics, with Cleveland (3-1) coming off a strong showing last year, finishing with the best record in the East at 64-18. They reached the playoffs but were knocked out in the second round. Meanwhile, Boston (1-3) also saw a second-round elimination in last year’s playoff run. Recent history shows these teams alternating wins and losses over their six most recent matchups, with the Cavaliers winning the last game.
Game Start Time: 7 p.m. ET at TD Garden, Boston. Latest betting lines have the Cavaliers favored by 3.5 points, with an over/under of 234.5 points.
Before making any bets on this match, be sure to check the detailed predictions and betting advice from the SportsLine Projection Model.
Betting Odds
- Spread: Cleveland -3.5 (DraftKings)
- Over/Under: 234.5 points
- Money Line: Cleveland -170, Boston +142
- Picks: See picks at SportsLine
- Streaming: Fubo (Try for free)
Why the Cavaliers Can Cover
The Cavaliers are coming off their best performance yet this season, securing a 21-point victory on the road against the Pistons. Donovan Mitchell was the star of the night, scoring 35 points on just 18 attempts, and every starter ended the game with double-digit points. Further bolstering their lineup, Evan Mobley, who was the league’s Defensive Player of the Year, recorded a strong performance with 15 points, 11 rebounds, 5 assists, and 3 blocks. Last season, the Cavaliers were ranked first offensively and are currently seventh for both defensive rating and points allowed.
Why the Celtics Can Cover
Despite facing some injuries and roster changes, the Celtics ranked second last season for points allowed and still hold the same position early this season, restricting opponents to the lowest shooting percentage from the field at 39.9%. In just their first win this year against New Orleans, Boston held their opponents to a mere 90 points after they had scored over 116 in previous games. Jaylen Brown has assumed a leading role with an average of 26 points per game, while the team’s depth contributed with a total of 65 points from starters and 57 from bench players during their last game.
Making Picks
The SportsLine Projection Model has run simulations for this game and suggests the total may lean towards the under with approximately 229 combined points projected. One side of the spread has a nearly 70% success rate according to their data. Find more details on SportsLine to stay ahead in your betting strategies.


