The second-ranked Indiana Hoosiers aim to maintain their perfect conference record against the Penn State Nittany Lions on Saturday. Indiana comes off a decisive 55-10 victory over Maryland, while Penn State suffered a 38-14 loss to Ohio State. Currently, Indiana has a 9-0 record, leading the Big Ten with a 6-0 conference tally, and remains unbeaten on the road this season, at 3-0. On the other hand, Penn State, with a disappointing 3-5 record and struggling through five consecutive losses, holds a 3-2 record at home.

Kickoff is set for noon ET at Beaver Stadium, with Penn State leading the all-time series 25-2, including the last match in 2023 where they triumphed 33-24. The latest odds show Indiana as 14.5-point favorites, with an over/under total set at 50.5 points as per the SportsLine consensus. Prior to making any bets on the Indiana vs. Penn State game, be sure to check out the college football predictions from the SportsLine Projection Model.

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The model simulates every FBS game 10,000 times and has generated over $2,000 in profit for $100 bettors on its top college football picks. Anyone following its betting picks on college football and on various betting sites can expect solid returns.

Reasons Why Indiana Could Cover
The Indiana offense is spearheaded by Heisman candidate Fernando Mendoza, the junior quarterback adjusting after transferring from California. Throughout nine starts, Mendoza has completed 72.3% of his passes totaling 2,124 yards and 25 touchdowns against just four interceptions. He’s also added significant yardage on the ground, with 220 rushing yards and four rushing touchdowns. His standout performance came in a 38-13 win against Michigan State when he completed 24 of 28 passes for 332 yards and four touchdowns.

Among Mendoza’s primary targets, junior wide receiver Omar Cooper Jr has caught 46 passes for 669 yards and eight touchdowns across nine games, contributing to a 56-9 blowout against Kennesaw State with a long rushing touchdown.

Reasons Why Penn State Could Cover
With senior quarterback Drew Allar sidelined due to a broken ankle, the Nittany Lions rely on freshman Ethan Grunkemeyer. Grunkemeyer, active in five games this season, has a passing completion rate of 62.7%, gathering 343 yards with one touchdown and three interceptions. His prior game against Ohio State saw him complete 19 of 28 attempts for 145 yards and one interception.

Senior back Kaytron Allen drives the ground game for Penn State, logging 688 yards and 10 touchdowns over eight games. In their close games against Iowa and UCLA, Allen showcased his scoring ability with two rushing touchdowns each.

How to Make Picks for Indiana vs. Penn State
The model predicts a score over the total, estimating 51 combined points, indicating that one side of the spread will likely succeed above 60% of the time based on its simulations. To dive deeper and see specific picks from the model, journey over to SportsLine.