
The Buffalo Bills are all set to clash with the Houston Texans on ‘Thursday Night Football.’ Recently, both teams have shown significant improvement in performance, each winning three out of their last four games. Currently, Buffalo holds a record of 7-3, positioning them second in the AFC East, while Houston stands at 5-5, sitting third in the AFC South.
In their last outing, the Bills emerged victorious against Tampa, scoring 44-32, largely due to Josh Allen’s remarkable six total touchdowns. Conversely, the Texans secured a 16-13 win over Tennessee, marking their second consecutive victory led by Davis Mills, who is filling in for C.J. Stroud, sidelined due to a concussion. Notably missing from the Bills’ lineup are tight end Dalton Kincaid and receiver Keon Coleman.
Kickoff for this highly anticipated match is scheduled for 8:15 p.m. ET at NRG Stadium, Houston. The Texans have a notable history against the Bills, having won five consecutive home games against them, including a close 23-20 win last season. The latest betting odds favor Buffalo by 5 points, shifting from an initial opening line of 2.5. The combined over/under for total points is set at 44.5.
Before placing any bets on the Bills vs. Texans, it’s worthwhile to consult SportsLine’s projection model, which simulates every NFL game 10,000 times and has demonstrated significant success in past predictions.
Predictions
Why the Bills can cover: Josh Allen has solidified his MVP status thanks to a stellar performance against the Bucs, with three passing and three rushing touchdowns to his name. Moreover, Buffalo’s rushing offense, led by James Cook, tops the league. The Bills are also a robust team defensively, particularly against aerial attacks, sitting in the top five for passing yards allowed and touchdowns given up.
Why the Texans can cover: The Texans’ defense is currently hailed as the best in football, excelling in scoring and total defense. Houston lacks vulnerabilities on defense, and their turnover differential (+7) gives them a critical edge. Historically, they have performed well against the Bills at home, holding a 5-0 record in their last five meetings.
How to Make Picks
For this matchup, the model suggests leaning towards the total points being under, projecting around 43 points.
Who comes out on top in this matchup? Visit [SportsLine] for detailed insights and recommended betting strategies based on the latest analysis.


