
Quarterback injuries are a major focus for NFL betting this Week 13, featuring key players either ruled out, returning, or questionable. Below are the most significant injuries and their implications on upcoming games.
Saints at Dolphins (1 PM ET)
- NO RB Alvin Kamara (knee, out)
- NO WR Chris Olave (back, questionable)
A struggling Saints team starting a rookie quarterback faces the Dolphins with star running back Alvin Kamara out and top receiver Chris Olave uncertain for the game. The Dolphins are favored by 5.5 points, and the total is set at 41.5.
Texans at Colts (1 PM ET)
- HOU QB C.J. Stroud (concussion, will play)
- IND QB Daniel Jones (fibula, will play)
Both teams will have their starting quarterbacks, which elevates the expectation for this AFC South game. The Colts are a 3.5-point favorite with a total of 44.5.
Falcons at Jets (1 PM ET)
- ATL WR Drake London (knee, out)
The Falcons continued struggles worsen as they enter this game without top receiver Drake London. Atlanta is a 2.5-point favorite with a total of 39.5.
49ers at Browns (1 PM ET)
- No major injuries reported.
Neither team reports significant injuries of note. The 49ers are favored by 4.5 points with a low total of 36.5.
Rams at Panthers (1 PM ET)
- CAR CB Jaycee Horn (concussion, out)
Losing star cornerback Jaycee Horn is crucial for the Panthers as they face a dynamic Rams offense. The Rams are 10.5-point favorites with a total of 45.
Jaguars at Titans (1 PM ET)
- JAX WR Brian Thomas Jr. (ankle, will play)
- TEN TE Chig Okonkwo (foot, questionable)
The Jaguars anticipate the return of Brian Thomas Jr. while Tennessee’s Chig Okonkwo’s status is uncertain. Jacksonville is a 6-point favorite with a total of 41.5.
Cardinals at Buccaneers (1 PM ET)
- AZ RB Trey Benson (ankle, out)
- AZ RB Emari Demercado (ankle, out)
- TB QB Baker Mayfield (shoulder, questionable)
Injury updates for Baker Mayfield and the Cardinals highlight this contest with serious implications. The Buccaneers are favored by 4.5 points.
Vikings at Seahawks (4:05 PM ET)
- MINN QB J.J. McCarthy (concussion, out)
With McCarthy ruled out, the Vikings turn to an undrafted rookie. Seattle is an 11.5-point favorite.
Bills at Steelers (4:25 PM ET)
- PITT QB Aaron Rodgers (wrist, will play)
The Steelers welcome Aaron Rodgers back against the Bills. Buffalo is a 3-point favorite with a total of 45.5.
Raiders at Chargers (4:25 PM ET)
- L.A. RB Omarion Hampton (ankle, out)
Chargers await the return of Hampton, while LA is favored by 9.5 points.
Broncos at Commanders (8:20 PM ET)
- WASH QB Jayden Daniels (elbow, out)
Daniels is sidelined this game, and Washington’s coach will starter in his absence. Denver is a 5.5-point favorite.
Giants at Patriots (8:15 PM ET, Monday)
- NYG QB Jaxson Dart (concussion, will play)
The Giants plan to utilize Dart in his return from injury against New England, who is favored by 7.5 points.
For regular updates on injuries leading up to kick-off, please keep an eye on this article.


