The Indianapolis Colts’ significant trade acquisition, Sauce Gardner, suffered a calf injury on the opening drive against the Houston Texans, forcing him to leave the game early.

Gardner was seen needing assistance as he approached the medical tent. Although he attempted to return to the locker room by himself, he ultimately required help. By the time the second quarter commenced, he reappeared on the sidelines dressed in street clothes and wearing a walking boot after the Colts announced his early exit due to the calf injury.

Sauce Gardner is in a walking boot and done for the day. — NFL on CBS 🏈 (@NFLonCBS) November 30, 2025

The Colts made a bold move to secure Gardner, trading away two first-round picks to the Jets at the trade deadline, signaling their intent to strengthen their defense for a playoff push following a strong offensive start to the season. Since that trade, the Colts hold a record of 1-1, including two overtime games, leading the Jaguars by one game and the Texans by two in the AFC South.

With Gardner’s swift exit due to his injury, there is growing concern for the Colts. Coach Shane Steichen is expected to provide further insight on the situation following the game.