The 2025 college football regular season culminates with the championship game between the No. 1 Ohio State Buckeyes and the No. 2 Indiana Hoosiers (12-0) on Saturday in the Big Ten Championship Game at Lucas Oil Stadium, Indianapolis.

The prestigious title, alongside the No. 1 seed for the College Football Playoff, and potentially the Heisman Trophy, are all at stake in this face-off. With a perfect record, the Buckeyes have advanced through the season with dominant performances, winning most games by comfortable margins.

Freshman quarterback Julian Sayin leads the nation in completion percentage at 78.9% and passing efficiency rating at 184.9.

Meanwhile, the Hoosiers have comparatively faced fewer contests with narrower margins, excelling with transfer quarterback Fernando Mendoza, who leads in passing touchdowns with 32 and ranks second in efficiency at 183.7.

According to leading sportsbooks, Ohio State enters this game as a 4-point favorite after opening at -6.5.

Curious about the movements in the lines or the impact of various games? Below are insights into former conference championship confrontations.

Texas Tech vs. BYU (noon)

Open: Texas Tech -11.5
Current: Texas Tech -12.5
In other games, moving through previous match-ups will also affect how teams compete as they head into the playoffs, such as with Miami (Ohio) and Western Michigan and other notable contests outlined above.

Now is the time for those interested in gambling to check out options at top sportsbooks such as DraftKings.