Duke vs. Michigan State Betting Preview for December 6, 2025
A deep dive into the upcoming match between Duke Blue Devils and Michigan State Spartans, featuring odds, predictions, and simulation insights.
The fourth-ranked Duke Blue Devils face off against the seventh-ranked Michigan State Spartans in an exciting matchup of unbeaten teams this Saturday. Duke recently secured a narrow victory over the 15th-ranked Florida Gators, winning 67-66, while Michigan State triumphed over Iowa with a 71-52 score.
- Date: December 6, 2025
- Time: 12:00 PM ET
- Location: Breslin Center, East Lansing, MI
- Duke’s Record: 9-0 (3-0 against ranked teams)
- Michigan State’s Record: 8-0 (3-0 against ranked teams)
Duke leads their all-time series against Michigan State 15-4, winning the last two encounters. According to the latest betting odds from SportsLine, Michigan State is a 1.5-point favorite, with the total points set at 139.5.
Betting Trends:
- Spread: Duke -1.5 at DraftKings
- Total Points: 139.5
- Money Line: Duke -116, Michigan State -103
The SportsLine Projection Model has simulated this matchup 10,000 times and has shown profitable returns over the last three seasons. For those interested in making picks for this game, check SportsLine for updated predictions.
