Michigan vs. Duke: 2026 Matchup Odds and Predictions
College Basketball/Sports

Michigan vs. Duke: 2026 Matchup Odds and Predictions

Preview of the highly anticipated college basketball clash between No. 3 Duke and top-ranked Michigan, scheduled for February 21, 2026.

An exciting non-conference college basketball tilt is set for Saturday as the No. 3 Duke Blue Devils face off against the top-ranked Michigan Wolverines in Washington, D.C. Michigan boasts a 25-1 record, with their sole defeat against Wisconsin. Meanwhile, Duke stands at 24-2, having lost to Texas Tech and North Carolina.

The game will tip off at 6:30 p.m. ET. The Wolverines are currently favored by 2.5 points, with the total set at 150.5. Before finalizing any bets on the Duke versus Michigan game, consider checking out the predictions and betting insights from the SportsLine Projection Model.

For new users, a special offer includes the DraftKings promo code, granting a $200 bonus if your initial $5+ wager wins.

The SportsLine Projection Model utilizes simulations to forecast each college basketball game, having recently achieved a remarkable 11-1 record on top-rated bets this season.

Currently, the model forecasts a total of 155 combined points in this matchup, indicating a strong likelihood of surpassing the over/under mark based on past performances from both teams.

Predictions for Duke vs. Michigan

The model predicts significant success for one side of the spread, hitting with over 60% accuracy historically. Visit SportsLine to check which side has the edge in this matchup.

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