Odds and Predictions for Arizona vs. Houston in College Basketball on February 21, 2026
A critical matchup in the Big 12 sees the Arizona Wildcats face the Houston Cougars, with both teams vying for top positions.
First place is on the line in the Big 12 when the fourth-ranked Arizona Wildcats battle the second-ranked Houston Cougars on Saturday. Arizona is coming off a 75-68 win over BYU, while Houston lost to Iowa State 70-67. The Wildcats (24-2, 11-2 Big 12) are 6-1 on the road this season. The Cougars (23-3, 11-2 Big 12) have yet to lose at home, leading the all-time series 8-6.
Koa Peat (lower leg) is out for Arizona, while Houston’s Kordel Jefferson (knee) is also unavailable. The game begins at 3 p.m. ET, with Houston favored by 5.5 points according to DraftKings, and an over/under set at 141.5 points.
Top Predictions: SportsLine’s model predicts that the total points will exceed 141.5, hitting the over in 70% of simulations. Arizona is projected to have key players reach double digits in scoring, with Brayden Burries averaging 13.4 points and Houston’s Emanuel Sharp projected at 18.3 points.
Betting Lines:
- Spread: Houston -5.5
- Total Points: 141.5
- Money Line: Houston -247, Arizona +199
For full predictions and betting advice, check out SportsLine.
