The top-ranked Duke Blue Devils are looking to keep their position at the pinnacle of the ACC as they face the Notre Dame Fighting Irish on Tuesday night, February 24, 2026. Duke recently secured a 68-63 victory over No. 1 Michigan, while Notre Dame fell to Pittsburgh with a score of 73-68 the same day.

Duke (25-2, 13-1 ACC) has been on a roll with four consecutive wins and boasts an 8-1 away record. Meanwhile, Notre Dame (12-15, 3-11 ACC) has struggled, particularly against ranked teams, holding an 0-4 record in such matchups while managing a 9-5 record at home.

Game start time is set for 7 p.m. ET at Purcell Pavilion in Notre Dame. The latest odds from DraftKings Sportsbook show Duke as a 17.5-point favorite, with an over/under for total points set at 139.5. Before placing bets on the matchup, readers are encouraged to check the SportsLine Projection Model for insights on sports predictions and betting advice.

The model simulates each college basketball game 10,000 times. It has a strong record, going 11-1 in its top-rated over/under picks recently and showing positive returns for its followers. When it comes to predictions, the model is forecasting Duke players to score a combined total of 149 points, suggesting that the over will hit in the majority of scenarios.

For more detailed betting insights and predictions, you can see the complete analysis at SportsLine.