The final regular-season Saturday of the college basketball season has arrived and rivalry matchups such as Duke vs. North Carolina, Alabama vs. Auburn, and Utah vs. BYU take center stage. Several conference tournaments are on the slate, with the Horizon, OVC, and Big Sky conferences set to crown champions this weekend. The latest college basketball odds show Auburn as a 7.5-point favorite, while Duke is favored by 10.5 in their respective matchups.

The first games start at noon ET, with the last tip-off of the day at 10 p.m. ET. As 2025 NCAA Tournament bids are on the line, which teams are at risk of upset? Before making any college basketball picks this Saturday, be sure to check the predictions from SportsLine’s proven computer model.

College Basketball Upset Picks for Saturday, March 8

Richmond (+205) vs. George Mason

The Spiders have struggled this season with an 8-20 record but have shown some resilience late in the season. Richmond achieved back-to-back upsets against Fordham and La Salle and was competitive in a prior loss (64-58) against George Mason. Sportsbook options include a +205 line for Richmond.

Stanford (+550) vs. Louisville

Stanford is currently riding a wave of success with three wins in four games. They will look to upset a Louisville team that has a winning streak of eight. However, Louisville could overlook this game in anticipation of the ACC Tournament. The model suggests Stanford keeps the game close, positioning the Cardinal as a viable underdog. The moneyline for Stanford stands at +550.

Eastern Washington (+150) vs. Northern Arizona

The Big Sky Tournament kicks off with an 8 vs. 9 matchup, where Eastern Washington finds itself slightly favored. Although the Eagles enter with a five-game losing streak, they previously had a four-game winning streak in February, which included two outright upsets. They have a slight advantage in shooting percentages and better defensive stats in steals and blocks. You can find Eastern Washington at +150 on various sportsbooks.

Want more college basketball picks for Saturday?

You have seen the model’s best longshot picks for Saturday. Get detailed spread, total, money-line, and prop picks for every game at SportsLine, all derived from a model that simulates every matchup 10,000 times.