
2025 NCAA Tournament Predictions: Surprising Upsets and Key Picks
A computer model simulating the March Madness bracket reveals potential major upsets in the upcoming tournament.
The 2025 NCAA Tournament bracket is set to kick off on Thursday, March 20, 2025, and expectations are running high following a series of unexpected outcomes in previous tournaments.
Overview
Last year saw the Big 12 struggling with major upsets, leading to all eight of their representatives exiting early. This year, however, the conference has gained strength by integrating four former Pac-12 programs, including the reputable Arizona, alongside teams like Kansas and Houston.
Surprising Predictions
One key upset the model predicts is that the first-round winner between North Carolina and San Diego State will eliminate the No. 6 seed Ole Miss. Both teams entered the tournament as 11 seeds, facing an Ole Miss team that has struggled defensively late in the season.
In another forecasting, Creighton is expected to upset Louisville in their matchup, with standout player Ryan Kalkbrenner paving the way. Kalkbrenner’s season has solidified his place in NCAA history as a formidable athlete.
Before making any bracket decisions, it’s advisable to check the bracket predictions from SportsLine’s computation model, which has proven accurate in identifying trends and upsets. Stay posted as the tournament unfolds, and follow the journey of Cinderellas and favorites alike into March Madness.