A No. 15 seed defeating a No. 2 seed in the NCAA Men’s Basketball tournament is not unheard of, with such upsets occurring in three of the past four tournaments. This year, St. John’s emerges as a strong contender, having closed the season with nine straight victories while Alabama remains the nation’s top scoring team.

Upset Rankings: 15 vs. 2

4. Omaha over St. John’s

Omaha faces a tough challenge against a seasoned St. John’s squad, needing a very cold shooting night from the Red Storm for any chance at victory.

3. Robert Morris over Alabama

While Alabama’s offense is formidable, Robert Morris brings a winning streak and offensive capabilities that could surprise, but they need to match up well.

2. Bryant over Michigan State

Bryant’s pace may cause issues for Michigan State, but the Spartans’ scoring ability should maintain an edge.

1. Wofford over Tennessee

Wofford has potential as a disruptive force if they can execute a slow-paced game against Tennessee, capitalizing on rebounds.