The 2024 NCAA Tournament bracket has been set, and the road to the Final Four has been laid out. The Auburn Tigers secured the No. 1 overall seed in the 2025 March Madness bracket, aiming for their second Final Four appearance and their first national championship. Auburn will begin its tournament journey against the winner of the Alabama State vs. St. Francis (PA) First Four game.

Will the Tigers, coached by Bruce Pearl, manage to cut down the nets in San Antonio? Can teams like Duke, Florida, or Alabama emerge as national champions? Before you finalize your 2025 March Madness bracket predictions, check out the picks from SportsLine’s proven computer model.

The model has simulated the tournament 10,000 times, accurately predicting many match outcomes including UConn’s recent championship run and nailing 13 teams in the Sweet 16 last year. Additionally, it has successfully identified 24 first-round upsets by double-digit seeds since its inception in 2016.

Three Games to Watch in the 2025 March Madness

1. Michigan vs. UC San Diego: No. 5 Michigan had a rough end to the regular season but caught fire in the Big Ten Tournament, securing a solid run to the No. 5 seed. Meanwhile, UC San Diego, in their first NCAA eligibility, stands out with a 30-4 record.

2. Louisville vs. Creighton: No. 8 Louisville’s turnaround season under first-year coach Pat Kelsey has been remarkable, while Creighton seeks to continue its streak of postseason victories.

3. Texas A&M vs. Yale: The No. 4 seed A&M looks to maintain their perfect Round of 64 record, but Yale’s offensive prowess could prove formidable.

With March Madness gearing up, the model’s predictions are set. To see the model’s optimal NCAA Tournament 2025 bracket, visit SportsLine.