As expected during March Madness, top seeds generally hold a winning record against lower seeds, but this trend ends when 8-seeds face 9-seeds, as 9-seeds have historically won more often. This year’s tournament features UConn, a defending champion and an 8-seed, who will face Oklahoma. Additionally, mid-major powerhouse Gonzaga, also an 8-seed, is set to take on 9-seed Georgia. Given the rankings, these matches are effectively toss-ups, but statistics favor the ninth-seeded teams slightly.

Moreover, there have been six instances of 9-seeds winning against No. 1 seeds in the second round historically, sparking intrigue around potential upsets in the first round.

Another notable matchup includes No. 7 Kansas against No. 10 Arkansas, which showcases two historically successful programs. Kansas is known for impressive Round of 64 performances but enters this year’s tournament as an underperforming No. 7 seed. Coach Calipari’s squad, on the other hand, could see the return of its second-leading scorer, adding to their depth.

Lastly, No. 5 Memphis will challenge No. 12 Colorado State. This game could prove crucial, as Memphis seeks its first victory under head coach Penny Hardaway in this round after achieving a remarkable non-conference win streak.