Saint Mary's vs. Vanderbilt Odds: March Madness 2025 Predictions Revealed
Basketball/NCAA Tournament/Sports

Saint Mary's vs. Vanderbilt Odds: March Madness 2025 Predictions Revealed

Analysis and betting odds for the NCAA tournament matchup between Saint Mary's Gaels and Vanderbilt Commodores.

The No. 7 seed Saint Mary’s Gaels (28-5) will face the No. 10 seed Vanderbilt Commodores (20-12) in the first round of the 2025 NCAA Tournament on Friday afternoon. Saint Mary’s clinched the WCC regular-season title, but Gonzaga avenged their earlier defeat in the WCC Tournament final. Vanderbilt, meanwhile, is looking for its first tournament advancement since 2017 under rookie head coach Mark Byington.

Game Details

  • Location: Rocket Arena, Cleveland
  • Tip-off: 3:15 p.m. ET
  • Current Odds: Saint Mary’s -4.5, Total: 135.5 points

Why Saint Mary’s Can Cover: Coach Randy Bennett’s experienced squad includes top seniors and has allowed only 60.7 points per game.

Why Vanderbilt Can Cover: Vanderbilt’s roster includes three solid scorers, improving their performance in a competitive SEC.

Model Prediction: The SportsLine model predicts a total of 143 combined points, offering unique insights into the matchup.

See the model’s picks here.

So, who will prevail between Saint Mary’s and Vanderbilt?

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