
MLB DFS: Key Strategies and Lineup Selections for MLB Opening Day 2025
Expert advice from daily Fantasy pro Mike McClure for crafting your optimal lineup on MLB Opening Day.
MLB Opening Day 2025 is finally here, with 14 games scheduled for Thursday. Notably, Juan Soto will make his debut with the New York Mets, facing the Houston Astros. Soto’s status as a leading slugger raises questions about his future performance, particularly with the favorable conditions at Citi Field.
McClure’s Top MLB DFS Picks
One key pick for the day is Bryce Harper of the Phillies, priced at $5,100 on DraftKings and $4,000 on FanDuel. Harper remains a dominant left-handed hitter, with impressive stats against left-handed pitchers and a favorable historical performance at Nationals Park, where the series will start.
In addition, Logan O’Hoppe, a promising catcher for the Angels, has an intriguing DFS profile at a budget-friendly price point, expanding roster flexibility in your lineups.
Engage with McClure’s insights and check out the comprehensive rankings and projections necessary for a successful opening day lineup.