When fierce competitors meet, it’s always a treat, and this Saturday night, the Houston Cougars will face the Duke Blue Devils in the 2025 NCAA Tournament Final Four. Houston cruised past Tennessee with a final score of 69-50 last Sunday, whereas Duke triumphed over Alabama 85-65.

Houston (34 wins, 4 losses) is on a 17-game winning streak, aiming for their first national championship and their seventh Final Four. Duke (35 wins, 3 losses) has also been impressive, winning 15 in a row, seeking their sixth national title with an 18th Final Four appearance.

Game Details:

• Tipoff: 8:49 p.m. ET from the Alamodome in San Antonio
• Odds: Duke is favored by 5.5 points. The over/under is set at 136.5 points. Duke’s money line stands at -269, while Houston sits at +216.

Key Players:

1. Duke: Freshman Cooper Flagg has excelled with averages of 18.9 points and 7.5 rebounds. Freshman guard Kon Knueppel has also been impressive with consecutive 20-point games in the last two matchups.
2. Houston: Senior guard L.J. Cryer is crucial, averaging 15.4 points with excellent shooting percentages. Meanwhile, junior guard Emanuel Sharp has tallied double-digit points in eight of the last nine games.

Model Predictions: The SportsLine projection model favors the combined points to exceed the total, forecasting 142 points. It indicates one side of the spread would prevail in over 50% of the simulations.

Check the complete model picks at SportsLine.