The following analysis previews the two-start pitchers for Fantasy Week 4 (April 14-20), highlighting Clay Holmes and Mitch Keller as key players to consider based on their matchups. A comprehensive look at their potential contributions is provided.

Context of Two-Start Pitchers

Each weekend, Scott White ranks the two-start pitchers for the upcoming scoring period and then categorizes them by how usable they are. Below are key considerations for the leading two-start pitchers this week.

Notable Two-Start Pitchers:

1. Tarik Skubal (SP, DET)

   • vs Milwaukee (Home)
   • @ Kansas City (Away)

2. Paul Skenes (SP, PIT)

   • vs Washington (Home)
   • @ Cleveland (Away)

3. Framber Valdez (SP, HOU)

   • @ St. Louis (Away)
   • vs San Diego (Home)

4. Max Fried (SP, NYY)

   • @ Kansas City (Away)
   • vs Tampa Bay (Home)

5. Dylan Cease (SP, SD)

   • @ Chicago Cubs (Away)
   • vs Houston (Home)

6. Luis Castillo (SP, SEA)

   • @ Cincinnati (Away)
   • @ Toronto (Away)

Conclusion

Max Fried, Jesus Luzardo, Jack Flaherty, and others present speculative opportunities this week based on their matchups. As with all fantasy considerations, adjustments may be required based on performance and health leading into the matchups.