The Wednesday MLB schedule offers multiple slates for DFS enthusiasts, highlighted by an exciting main slate. Ten games commence after 6:45 p.m. ET, featuring significant players in the MLB DFS arena. Notably, the Cubs will take on the Dodgers once more after a tightly contested match on Tuesday that ended 11-10 in the Cubs’ favor. Ten players from that matchup had multiple hits, making those players prime candidates for DFS lineups.

Given that Shohei Ohtani from the Dodgers and Kyle Tucker from the Cubs rank among the top-priced players, should you devote a substantial part of your budget to them this Wednesday? Before settling on your MLB DFS choices for the day, make sure to review insights and projections provided by Mike McClure, a well-regarded fantasy professional with over $2 million in winnings, at SportsLine.

On the previous Tuesday, McClure pinpointed Wyatt Langford, an outfielder for the Texas Rangers, as a key education for DFS lineups, resulting in a remarkable performance of 3-for-4 at bat, with a home run, generating significant fantasy points. He is again featured among the recommended players for today.

As the 2025 MLB season advances, tune in to see McClure’s top daily fantasy picks for April 23. For a complete insight and more recommendations, visit SportsLine.