
The NFL has announced that the Philadelphia Eagles will host the Dallas Cowboys on Thursday, September 4, for the 2025 season opener. Early betting lines show the Eagles favored by 6.5 to 7 points, with the game total at 46.5 to 47. Some sportsbooks have also released player props, with FanDuel offering -115 odds for Saquon Barkley to rush for 100 yards and DraftKings including various anytime touchdown options.
For those wanting to support the Eagles, FanDuel offers a point spread of -6.5 on the day of the announcement, albeit at -120 instead of the usual -110. Meanwhile, DraftKings reportedly has the best money line at -298, suggesting a victory for the defending champions, while others set their lines at -310 or higher.
Cowboys vs. Eagles Best Bets
- Eagles -6.5 (-120, FanDuel)
- Dak Prescott 300+ passing yards (+350, FanDuel)
- Cowboys team total Under 20.5 (-142, DraftKings) and 17.5 (+114, DraftKings)
- DeVonta Smith anytime touchdown (+160, DraftKings)
Expect the Eagles to aim for a comfortable position against the Cowboys, who might face tough challenges based on previous performances."