There are 15 games on the Saturday MLB schedule, starting at 2:20 p.m. ET, with key matchups such as Braves vs. Red Sox and Yankees vs. Dodgers. Atlanta is currently favored at -184 (bet $184 to win $100) against Boston, while the Yankees face a slight -123 against the Dodgers.
Additionally, bettors are turning toward underdogs that may surprise on Saturday. The Nationals (+190) defeated the Diamondbacks on Friday and are now positioned as +165 underdogs in their next matchup. The SportsLine model is keen on the Nationals, along with stronger prospects like the Rangers (+128) and Pirates (+184).
Before making any MLB selections or assembling your betting slips, be sure to check the predictions and advice from SportsLine’s simulation model. You can also view the latest MLB Props Picks and our top MLB Home Run Picks for Saturday.
The SportsLine Projection Model simulates each MLB game 10,000 times. Currently, it’s entering Week 10 of the 2025 season on a successful run of 27-21 (56%) with top MLB betting selections. Following this model could yield significant returns.
Here are Saturday’s best bets:
- Rangers money line vs. Cardinals (+128)
- Brewers run line +1.5 vs. Phillies (-136)
- Pirates money line vs. Padres (+184)
Combining these selections into an MLB parlay at DraftKings Sportsbook yields a payout of +1063 (odds may vary). New users can take advantage of a DraftKings promo code that grants $300 in bonus bets with a $5 wager.
Rangers Money Line vs. Cardinals (+128)
The Rangers previously triumphed in Game 1 of this series, securing an 11-1 victory despite initially being underdogs. They aim to retain this offensive pace in Game 2. Texas starter Patrick Corbin holds a 3.75 ERA, while the Cardinals’ Sonny Gray has a 6.75 ERA on the road this season. In simulations, the model grants a substantial win probability to Texas as the home underdogs.
Brewers Run Line +1.5 vs. Phillies (-136)
While the Phillies’ recent form has dipped, with three losses in their last five, the Brewers are on a five-game winning streak. The prediction model forecasts a close victory for Philadelphia by just 0.3 runs, leading to a 70% confidence in the Brewers covering this run line.
Pirates Money Line vs. Padres (+184)
Pittsburgh performed well during its West Coast series. They previously defeated Arizona in two of three games and narrowly lost Game 1 against San Diego. The model indicates a tightly contested game, giving Pittsburgh strong value at +184.
Want more MLB predictions for today?
You’ve witnessed some of the model’s best bets for Saturday. To get further run line, total, and money line picks for every game, click here to access the comprehensive simulations.
