Runs were scarce in the first game of the Yankees vs. Red Sox matchup, but expectations are for a shift in Game 2 of their weekend series scheduled for Saturday at 7:15 p.m. ET. The starting pitchers will be Hunter Dobbins and Carlos Rodon, who were also on the mound for last week’s game that saw a total of 18 runs scored. This is a significant reason why SportsLine’s model predicts more than 8.5 total runs in the upcoming Red Sox vs. Yankees game.
On the 15-game Saturday MLB slate, the model supports two underdog teams: it favors the Angels +1.5 on the run line (-153) against the Orioles and backs the Twins (-105) to win outright against the Astros. Before finalizing any MLB bets or creating parlay bets, it’s recommended to check the predictions and betting tips from SportsLine’s trusted computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times. Currently, it has achieved a 27-23 record for top-rated MLB side bets at the top of Week 12 in the 2025 MLB season. Over the past couple of months, it has particularly excelled with home run prop predictions, yielding a profit of more than 35 units. Anyone who follows the model on sportsbooks and betting apps might have seen impressive returns.
The model has assessed the MLB odds for Saturday and has unveiled its top MLB picks. Combining these three predictions into a parlay at DraftKings Sportsbook could yield a +530 payout based on a risk of $100 to win $530. New users can even benefit from the DraftKings promo code which offers $300 in bonus bets instantly with a $5 wager.
Here are the model’s primary bets for the MLB slate on Saturday:
- Angels run line +1.5 vs. Orioles (-153)
- Twins money line vs. Astros (-105)
- Over 8.5 in Yankees vs. Red Sox (-105)
Combining these selections offers a chance at a payout of +530 (odds may vary).
Angels run line +1.5 vs. Orioles (-153)
Left-handed pitchers have triumphed over the Orioles this season, with Baltimore recording just 4 wins and 15 losses against southpaws. Los Angeles has Tyler Anderson starting, who managed to limit the Orioles to just one earned run over five innings in their earlier encounter this season while striking out five. Another impressive performance is anticipated, which should help the Angels stay within the run line in this encounter. The model estimates the likelihood of a cover by Los Angeles at nearly 70%, marking it as a high-confidence pick.
Twins money line vs. Astros (-105)
In the anticipated 4:10 p.m. ET duel, top starting pitchers Hunter Brown for the Astros and Joe Ryan for the Twins will go head to head. Oddsmakers predict it to be a low-scoring contest, with the over/under set at 7 runs. Given the expectation of a close game with limited offense, the model leans in favor of Ryan and the Twins. Ryan boasts an impressive 2.93 ERA on the road, facing a slightly weakened Astros lineup missing Yordan Alvarez (hand) and possibly Isaac Paredes, who was out with a hamstring issue. The Twins win nearly 49% of simulations, making them a prudent choice at this betting price.
Over 8.5 in Yankees vs. Red Sox (-105)
The Red Sox won Game 1 by a tight score of 2-1 on Friday, easily hitting the Under 8 in that match. However, last week’s series showcased explosive offense, and the model foresees a return to that form for Game 2. In their recent matches, these teams scored a total of 15, 17, and 18 runs, surpassing the total runs in all three games. The model anticipates approximately 10.4 runs in this rivalry match, exceeding the total in more than 60% of simulations.
For those seeking more MLB insights for today, you can find more detailed betting predictions, including run line, total, and money-line picks for all games here, sourced from a model that has simulated each match 10,000 times.
