
The Washington Nationals aim to secure their second consecutive victory against the San Diego Padres in the ongoing series this Tuesday. After a triumph with a score of 10-6 on Monday, Washington plans to send right-handed pitcher Trevor Williams (3-8, 5.54 ERA) to the mound, while Ryan Bergert (1-0, 1.88 ERA) will take the lead for San Diego.
First pitch is slated for 9:40 PM ET at Petco Park in San Diego. Currently, San Diego is favored at -169 (bet $169 to win $100) according to the latest odds from DraftKings Sportsbook. The total runs scored are estimated at nine, with Jackson Merrill projected at -390 for over 0.5 hits, and James Wood at +330 for a home run. For further insights, explore our Tuesday MLB prop picks and home run picks.
The SportsLine Projection Model has simulated this matchup 10,000 times and is currently on a 41-32 record with top-rated MLB money-line betting picks this season. Shrewd bettors should follow at reputable sportsbooks and betting apps for optimal returns.
Top betting predictions for the Nationals vs. Padres:
- Nationals ML (+140)
- Nationals run line +1.5 (-148)
- Brady House over 0.5 total bases (-175)
Nationals to win (+140)
Washington aims to clinch the series and seeks its fourth victory in the last six games, while San Diego is coming off five losses in the past eight matches. According to analysis, the model predicts a money line probability exceeding 40%, rating it a ‘C’. FanDuel offers a +142 price on the Nationals, allowing for enhanced returns for new users with the potential value from a FanDuel promo code.
Nationals run line +1.5 (-148)
Model simulations suggest that Washington can cover the proposed run line, with the Padres predicted to lead by an average score of 4.7 to 4.4, allowing the Nationals to cover well over 60% of simulations, indicating great value. As of 2025, the Nationals’ record on the road stands at 17-22, while the Padres are 23-14 at home.
For those wishing for additional MLB betting insights, follow the expert Matt Severance from SportsLine, who has an impressive record of 170-96 on his last 266 MLB betting predictions.