The Toronto Blue Jays will look to secure the series win when they battle the San Francisco Giants on Saturday afternoon, having won 4-0 in Friday’s opener. The Giants (52-46) are set to start right-hander Logan Webb (9-6, 2.94 ERA), while the Blue Jays (56-41) will send left-hander Eric Lauer (4-2, 2.78 ERA) to the mound.
First pitch from Rogers Centre in Toronto is slated for 3:07 PM ET. San Francisco is -124 on the money line (risk $124 to win $100), while Toronto is +104 (risk $100 to win $104). The over/under for total runs scored is set at 8. Lauer is -135 to record 4.5+ strikeouts, while Vladimir Guerrero Jr. is +500 to hit a home run.
The SportsLine Projection Model has simulated every MLB game 10,000 times, entering Week 17 of the 2025 MLB season with a 46-43 record on top-rated MLB betting picks. Here are the model’s three best bets for the Giants vs. Blue Jays:
- Blue Jays ML (+104)
- Bo Bichette over 1.5 total bases (-120)
Bo Bichette Projection
Bichette has been outstanding, recording hits in nine of his last ten games. He is hitting .280 with 25 doubles, one triple, and 12 homers across 94 games this season.
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