The Washington Nationals are set to face the Cincinnati Reds at their home ground, Nationals Park, on Wednesday for the concluding match of their mid-week series.
The Nationals have taken the lead in the series by winning the first two encounters, including a commanding 6-1 victory on Tuesday, highlighted by a home run from Josh Bell. Overall, Washington stands at 41-60 and 21-30 at home, while the Reds maintain a record of 52-50 with a 24-28 away performance this season. Nick Lodolo is anticipated to be the starting pitcher for the Reds with a record of 7-6 and 3.33 ERA, whereas the Nationals will feature Michael Soroka, who has a 3-7 record and a 5.10 ERA.
The game is slated to commence at 12:05 PM ET. According to the latest odds, Cincinnati is favored at -140 on the money line (bet $140 to earn $100), with the predicted total for runs set at 9.
Before making any picks for the Reds vs. Nationals matchup, check out the reliable predictions and betting insights from SportsLine’s advanced computer simulation model.
The simulation model has completed 10,000 simulations for this MLB game, and it stands 46-43 on high-stakes MLB picks entering Week 17 of the 2025 MLB season.
Why the Reds can win: The Reds are intensely competing in the National League playoff race. They are keen on reversing their three-game losing streak in this pivotal final match. Currently, they have the sixth-best run differential in the National League at +35. Elly De La Cruz, a two-time MLB All-Star, leads the Reds with an impressive record of .279 batting average, 18 home runs, 65 RBIs, and 26 stolen bases.
Why the Nationals can win: Despite sitting at the bottom of the National League East, the Nationals have recently found form, securing three wins from five games since the All-Star break. They’ve demonstrated dominance in these initial two matchups of the series, restricting the Reds’ scoring in a strong defensive showing on Tuesday.
Key offensive players for the Nationals include James Wood and CJ Abrams. Wood holds a batting average of .272, boasting 24 home runs and 70 RBIs, while Abrams maintains a .279 average with 13 home runs and 37 RBIs.
How to make picks: SportsLine’s model is favoring the Over for total runs, predicting a combined total of 9.5 runs this matchup, and indicates one side of the money line performs well in over 60% of simulations. Find detailed predictions and insights on SportsLine’s site for further guidance.
So who ultimately triumphs in the Reds vs. Nationals matchup, and which side of the money line proves victorious over 60% of the time? Visit SportsLine now to discover the favored side, relying on the model that has excelled at its MLB predictions.
