The college football season of 2025 kicks off with Week 0 scheduled for Saturday, August 23. The highlight is a Big 12 clash in Ireland between Kansas State and Iowa State, marking the tenth such game hosted there. Kansas State is favored by 3.5 points in the latest odds.

Other notable matchups include Kansas as 14-point favorites against Fresno State and Hawaii at -2.5 against Stanford. Additionally, Sam Houston faces Western Kentucky at -9.5 in another significant tilt between Group of Five squads.

Before committing to any betting choices for this pre-season week, check out the betting insights from renowned Vegas handicapper Bruce Marshall. He has a history of successful bets, including a 64-43 record last season, demonstrating his insights on college football betting.

One of his prime recommendations includes backing Fresno State at +13.5 against Kansas in their 6:30 p.m. ET matchup, based on historical performance and trends.

College Football Odds for Week 0

• Iowa State vs. Kansas State (-3, 49.5)
• Kansas vs. Fresno State (+13.5, 51.5)
• Sam Houston vs. Western Kentucky (-9.5, 60.5)
• Stanford vs. Hawaii (-2.5, 53.5)

For more details on each match up and insights from Bruce Marshall, visit the full betting guide.